r'(?<address>^\d{1,5}\s[a-zA-z\s]+,\s[a-zA-z]+,\s[A-Z]{,2}$)'This is about as strict as it gets.
Basically what it does is:
makes sure it starts with a number
makes sure the the number is max 5 digits long(not sure who long this can go to, adjust{1,5} if needed
makes sure comma, space and street name follows
makes sure comma, space and city name follows
makes sure comma, state follows and it ends with state